This is the official page for the City of Independence, Missouri. The City of Independence is home to great American stories. Independence, the starting point for pioneers during westward expansion and President Harry S. Truman’s hometown, has served as the backdrop to individuals as they blaze trails and make history. Today, Independence has a population of approximately 120,000, covering 78 square miles in Eastern Jackson County, and is the fifth largest city in Missouri. Minutes from Kansas City, Independence offers individuals and families a hometown feel with big city amenities. It's a place of friendly people, bustling businesses, and opportunities. Come and write your great American story alongside ours.