The Pasteur Network is an alliance of over 30 institutes which plays a crucial role in tackling global health challenges through science, innovation and public health. Its distinctive strength lies in the diversity and extensive geographic reach, spanning 25 countries across 5 continents, fostering a dynamic community of knowledge and expertise. The Pasteur Network is recognized as a WHO non-state actor, and members of the network are frequently embedded into local Ministries of Health. The PN sustains a global infrastructure encompassing 50+ national and regional reference laboratories, which includes multiple Biosafety Level 3 Laboratories, and 17 WHO Collaborating Centers. The Pasteur Network's work is guided by four strategic pillars: 1) Epidemic Preparedness, Intelligence, with focus on Climate sensitive diseases, 2) Research, Development, and Innovation, 3) Knowledge Communities, and 4) Good Governance and Equity.